Human cardiosphere-derived stromal cells exposed to SARS-CoV-2 evolve into hyper-inflammatory/pro-fibrotic phenotype and produce infective viral particles depending on the levels of ACE2 receptor expression

AIMS: Patients with severe respiratory syndrome caused by SARS-CoV-2 undergo cardiac complications due to hyper-inflammatory conditions. Although the presence of the virus has been detected in the myocardium of infected patients, and infection of induced pluripotent cells-derived cardiomyocytes has...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Amendola, Alessandra, Garoffolo, Gloria, Songia, Paola, Nardacci, Roberta, Ferrari, Silvia, Bernava, Giacomo, Canzano, Paola, Myasoedova, Veronika, Colavita, Francesca, Castilletti, Concetta, Sberna, Giuseppe, Capobianchi, Maria Rosaria, Piacentini, Mauro, Agrifoglio, Marco, Colombo, Gualtiero I, Poggio, Paolo, Pesce, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7989620/
https://ncbi.nlm.nih.gov/pubmed/33705542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvab082
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