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Dietary saturated fatty acid palmitate promotes cartilage lesions and activates the unfolded protein response pathway in mouse knee joints

Increased intake of dietary saturated fatty acids has been linked to obesity and the development of Osteoarthritis (OA). However, the mechanism by which these fats promote cartilage degradation and the development of OA is not clearly understood. Here, we report the effects of consumption of common...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Tan, Li, Harper, Lindsey R., Armstrong, Alexandra, Carlson, Cathy S., Yammani, Raghunatha R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7899342/
https://ncbi.nlm.nih.gov/pubmed/33617553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247237
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