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High Fat-Diet and Saturated Fatty Acid Palmitate Inhibits IGF-1 Function in Chondrocytes
INTRODUCTION: Insulin-like growth factor-1 (IGF-1) promotes matrix synthesis and cell survival in cartilage. Chondrocytes from aged and osteoarthritic cartilage have a reduced response to IGF-1. The purpose of this study was to determine the effect of free fatty acids present in a high-fat diet on I...
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| Publicado no: | Osteoarthritis Cartilage |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5565687/ https://ncbi.nlm.nih.gov/pubmed/28545881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2017.05.011 |
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