F344/NTac Rats Chronically Exposed to Bromodichloroacetic Acid Develop Mammary Adenocarcinomas With Mixed Luminal/Basal Phenotype and Tgfβ Dysregulation

Breast cancer is the most common cancer, and the second-leading cause of cancer mortality in women in the United States. A recent 2-year National Toxicology Program (NTP) carcinogenicity study showed an increased incidence of proliferative mammary lesions (hyperplasia, fibroadenoma, adenocarcinoma)...

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Pubblicato in:Vet Pathol
Autori principali: Harvey, Janice B., Hong, Hue-Hua L., Bhusari, Sachin, Ton, Thai-Vu, Wang, Yu, Foley, Julie F., Peddada, Shyamal D., Hooth, Michelle, DeVito, Michael, Nyska, Abraham, Pandiri, Arun R., Hoenerhoff, Mark J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7899196/
https://ncbi.nlm.nih.gov/pubmed/25732176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300985815571680
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