Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm

AIMS: Angiotensin II (AngII) is a potential contributor to the development of abdominal aortic aneurysm (AAA). In aortic vascular smooth muscle cells (VSMCs), exposure to AngII induces mitochondrial fission via dynamin-related protein 1 (Drp1). However, pathophysiological relevance of mitochondrial...

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Bibliografiske detaljer
Udgivet i:Cardiovasc Res
Main Authors: Cooper, Hannah A, Cicalese, Stephanie, Preston, Kyle J, Kawai, Tatsuo, Okuno, Keisuke, Choi, Eric T, Kasahara, Shingo, Uchida, Haruhito A, Otaka, Nozomu, Scalia, Rosario, Rizzo, Victor, Eguchi, Satoru
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898955/
https://ncbi.nlm.nih.gov/pubmed/32384150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvaa133
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