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Total Synthesis and Structure Revision of Halioxepine

The first total synthesis of halioxepine is accomplished using a 1,4‐addition for constructing the quaternary center at C10 and a halo etherification for the generation of the tertiary ether at C7. The correct structure of halioxepine was determined by assembling different enantiomeric building bloc...

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Publicat a:Chemistry
Autors principals: Poock, Caroline, Kalesse, Markus
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898713/
https://ncbi.nlm.nih.gov/pubmed/33215739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202004847
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