Hepatitis B Virus–Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma

BACKGROUND AND AIMS: Hepatitis B virus (HBV) integrations are common in hepatocellular carcinoma (HCC). In particular, alterations of the telomerase reverse transcriptase (TERT) gene by HBV integrations are frequent; however, the molecular mechanism and functional consequence underlying TERT HBV int...

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Bibliographische Detailangaben
Veröffentlicht in:Hepatology
Hauptverfasser: Sze, Karen Man‐Fong, Ho, Daniel Wai‐Hung, Chiu, Yung‐Tuen, Tsui, Yu‐Man, Chan, Lo‐Kong, Lee, Joyce Man‐Fong, Chok, Kenneth Siu‐Ho, Chan, Albert Chi‐Yan, Tang, Chung‐Ngai, Tang, Victor Wai‐Lun, Lo, Irene Lai‐Oi, Yau, Derek Tsz‐Wai, Cheung, Tan‐To, Ng, Irene Oi‐Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898544/
https://ncbi.nlm.nih.gov/pubmed/32170761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31231
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