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Sex Differences in Gene Expression and Regulatory Networks across 29 Human Tissues

Sex differences manifest in many diseases and may drive sex-specific therapeutic responses. To understand the molecular basis of sex differences, we evaluated sex-biased gene regulation by constructing sample-specific gene regulatory networks in 29 human healthy tissues using 8,279 whole-genome expr...

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Publicat a:Cell Rep
Autors principals: Lopes-Ramos, Camila M., Chen, Cho-Yi, Kuijjer, Marieke L., Paulson, Joseph N., Sonawane, Abhijeet R., Fagny, Maud, Platig, John, Glass, Kimberly, Quackenbush, John, DeMeo, Dawn L.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898458/
https://ncbi.nlm.nih.gov/pubmed/32579922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107795
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