Regulatory network changes between cell lines and their tissues of origin

BACKGROUND: Cell lines are an indispensable tool in biomedical research and often used as surrogates for tissues. Although there are recognized important cellular and transcriptomic differences between cell lines and tissues, a systematic overview of the differences between the regulatory processes...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Genomics
Main Authors: Lopes-Ramos, Camila M., Paulson, Joseph N., Chen, Cho-Yi, Kuijjer, Marieke L., Fagny, Maud, Platig, John, Sonawane, Abhijeet R., DeMeo, Dawn L., Quackenbush, John, Glass, Kimberly
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596945/
https://ncbi.nlm.nih.gov/pubmed/28899340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4111-x
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