Wordt geladen...
Structural Basis of the Modulation of the Voltage‐Gated Calcium Ion Channel Ca(v)1.1 by Dihydropyridine Compounds
1,4‐Dihydropyridines (DHP), the most commonly used antihypertensives, function by inhibiting the L‐type voltage‐gated Ca(2+) (Ca(v)) channels. DHP compounds exhibit chirality‐specific antagonistic or agonistic effects. The structure of rabbit Ca(v)1.1 bound to an achiral drug nifedipine reveals the...
Bewaard in:
| Gepubliceerd in: | Angew Chem Int Ed Engl |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2020
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7898392/ https://ncbi.nlm.nih.gov/pubmed/33125829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202011793 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|