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Nicotinic receptor pharmacology in silico: Insights and challenges
Nicotinic acetylcholine receptors (nAChR) are homo- or hetero-pentameric ligand-gated ion channels of the Cys-loop superfamily and play important roles in the nervous system and muscles. Studies on nAChR benefit from in silico modeling due to the lack of high-resolution structures for most receptor...
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| Publicado no: | Neuropharmacology |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7898244/ https://ncbi.nlm.nih.gov/pubmed/32738311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2020.108257 |
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