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High levels of gut-homing immunoglobulin A(+) B lymphocytes support the pathogenic role of intestinal mucosal hyperresponsiveness in immunoglobulin A nephropathy patients

BACKGROUND: Immunoglobulin A nephropathy (IgAN) is the most frequent primary glomerulonephritis. The role of the microbiota and mucosal immunity in the pathogenesis of IgAN remains a key element. To date, the hypothetical relationship between commensal bacteria, elevated tumour necrosis factor (TNF)...

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Dades bibliogràfiques
Publicat a:Nephrol Dial Transplant
Autors principals: Sallustio, Fabio, Curci, Claudia, Chaoul, Nada, Fontò, Giulia, Lauriero, Gabriella, Picerno, Angela, Divella, Chiara, Di Leo, Vincenzo, De Angelis, Maria, Ben Mkaddem, Sanae, Macchia, Luigi, Gallone, Anna, Monteiro, Renato C, Pesce, Francesco, Gesualdo, Loreto
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898021/
https://ncbi.nlm.nih.gov/pubmed/33200215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfaa264
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