Exosome-functionalized polyetheretherketone-based implant with immunomodulatory property for enhancing osseointegration

The host immune response effecting on biomaterials is critical to determine implant fates and bone regeneration property. Bone marrow stem cells (BMSCs) derived exosomes (Exos) contain multiple biosignal molecules and have been demonstrated to exhibit immunomodulatory functions. Herein, we develop a...

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Pubblicato in:Bioact Mater
Autori principali: Fan, Lei, Guan, Pengfei, Xiao, Cairong, Wen, Huiquan, Wang, Qiyou, Liu, Can, Luo, Yian, Ma, Limin, Tan, Guoxin, Yu, Peng, Zhou, Lei, Ning, Chengyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: KeAi Publishing 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897935/
https://ncbi.nlm.nih.gov/pubmed/33665507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioactmat.2021.02.005
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