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Immunomodulatory Peptide IDR-1018 Decreases Implant Infection and Preserves Osseointegration

BACKGROUND: Innate defense regulator peptide-1018 (IDR-1018) is a 12-amino acid, synthetic, immunomodulatory host defense peptide that can reduce soft tissue infections and is less likely to induce bacterial resistance than conventional antibiotics. However, IDRs have not been tested on orthopaedic...

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Detalhes bibliográficos
Publicado no:Clin Orthop Relat Res
Main Authors: Choe, Hyonmin, Narayanan, Arvind S., Gandhi, Deep A., Weinberg, Aaron, Marcus, Randall E., Lee, Zhenghong, Bonomo, Robert A., Greenfield, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523515/
https://ncbi.nlm.nih.gov/pubmed/25953690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-015-4301-2
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