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Immunomodulatory Peptide IDR-1018 Decreases Implant Infection and Preserves Osseointegration

BACKGROUND: Innate defense regulator peptide-1018 (IDR-1018) is a 12-amino acid, synthetic, immunomodulatory host defense peptide that can reduce soft tissue infections and is less likely to induce bacterial resistance than conventional antibiotics. However, IDRs have not been tested on orthopaedic...

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Bibliografiska uppgifter
I publikationen:Clin Orthop Relat Res
Huvudupphovsmän: Choe, Hyonmin, Narayanan, Arvind S., Gandhi, Deep A., Weinberg, Aaron, Marcus, Randall E., Lee, Zhenghong, Bonomo, Robert A., Greenfield, Edward M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer US 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523515/
https://ncbi.nlm.nih.gov/pubmed/25953690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-015-4301-2
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