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JF1/B6F1 Ngly1(−/−) mouse as an isogenic animal model of NGLY1 deficiency
N-Glycanase 1 (NGLY1) deficiency is a congenital disorder caused by mutations in the NGLY1 gene. Because systemic Ngly1(−/−) mice with a C57BL/6 (B6) background are embryonically lethal, studies on the mechanism of NGLY1 deficiency using mice have been problematic. In this study, B6-Ngly1(−/+) mice...
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| Publicado no: | Proc Jpn Acad Ser B Phys Biol Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Japan Academy
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7897899/ https://ncbi.nlm.nih.gov/pubmed/33563880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.97.005 |
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