Heterozygous P32/C1QBP/HABP1 Polymorphism rs56014026 Reduces Mitochondrial Oxidative Phosphorylation and Is Expressed in Low-grade Colorectal Carcinomas

Rapid proliferation of cancer cells is enabled by favoring aerobic glycolysis over mitochondrial oxidative phosphorylation (OXPHOS). P32 (C1QBP/gC1qR) is essential for mitochondrial protein translation and thus indispensable for OXPHOS activity. It is ubiquitously expressed and directed to the mitoc...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Oncol
Päätekijät: Raschdorf, Annika, Sünderhauf, Annika, Skibbe, Kerstin, Ghebrehiwet, Berhane, Peerschke, Ellinor I., Sina, Christian, Derer, Stefanie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2021
Aiheet:
Oncology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897657/
https://ncbi.nlm.nih.gov/pubmed/33628739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.631592
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