GC1qR Cleavage by Caspase-1 Drives Aerobic Glycolysis in Tumor Cells

Self-sustained cell proliferation constitutes one hallmark of cancer enabled by aerobic glycolysis which is characterized by imbalanced glycolysis and mitochondrial oxidative phosphorylation (OXPHOS) activity, named the Warburg effect. The C1q binding protein (C1QBP; gC1qR) is pivotal for mitochondr...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Sünderhauf, Annika, Raschdorf, Annika, Hicken, Maren, Schlichting, Heidi, Fetzer, Franziska, Brethack, Ann-Kathrin, Perner, Sven, Kemper, Claudia, Ghebrehiwet, Berhane, Sina, Christian, Derer, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7556196/
https://ncbi.nlm.nih.gov/pubmed/33102234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.575854
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