To mock or not: a comprehensive comparison of mock IP and DNA input for ChIP-seq

Chromatin immunoprecipitation (IP) followed by sequencing (ChIP-seq) is the gold standard to detect transcription-factor (TF) binding sites in the genome. Its success depends on appropriate controls removing systematic biases. The predominantly used controls, i.e. DNA input, correct for uneven sonic...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Xu, Jinrui, Kudron, Michelle M, Victorsen, Alec, Gao, Jiahao, Ammouri, Haneen N, Navarro, Fabio C P, Gevirtzman, Louis, Waterston, Robert H, White, Kevin P, Reinke, Valerie, Gerstein, Mark
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
Assuntos:
Methods Online
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897498/
https://ncbi.nlm.nih.gov/pubmed/33347581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1155
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