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Parallel monitoring of RNA abundance, localization and compactness with correlative single molecule FISH on LR White embedded samples

Single mRNA molecules are frequently detected by single molecule fluorescence in situ hybridization (smFISH) using branched DNA technology. While providing strong and background-reduced signals, the method is inefficient in detecting mRNAs within dense structures, in monitoring mRNA compactness and...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Kramer, Susanne, Meyer-Natus, Elisabeth, Stigloher, Christian, Thoma, Hanna, Schnaufer, Achim, Engstler, Markus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897490/
https://ncbi.nlm.nih.gov/pubmed/33275141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1142
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