Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells

BACKGROUND: Glutaminase isoenzymes GLS and GLS2 play apparently opposing roles in cancer: GLS acts as an oncoprotein, while GLS2 (GAB isoform) has context specific tumour suppressive activity. Some microRNAs (miRNAs) have been implicated in progression of tumours, including gliomas. The aim was to i...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: de los Santos-Jiménez, Juan, Campos-Sandoval, José A., Márquez-Torres, Clara, Urbano-Polo, Nieves, Brøndegaard, David, Martín-Rufián, Mercedes, Lobo, Carolina, Peñalver, Ana, Gómez-García, María C., Martín-Campos, Janet, Cardona, Carolina, Castilla, Laura, da Costa Souza, Felipe, Cheng, Tzuling, Segura, Juan A., Alonso, Francisco J., Curi, Rui, Colquhoun, Alison, DeBerardinis, Ralph J., Márquez, Javier, Matés, José M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897386/
https://ncbi.nlm.nih.gov/pubmed/33610185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-021-00712-y
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