Mammalian Glutaminase Gls2 Gene Encodes Two Functional Alternative Transcripts by a Surrogate Promoter Usage Mechanism

BACKGROUND: Glutaminase is expressed in most mammalian tissues and cancer cells, but the regulation of its expression is poorly understood. An essential step to accomplish this goal is the characterization of its species- and cell-specific isoenzyme pattern of expression. Our aim was to identify and...

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Bibliografiska uppgifter
Huvudupphovsmän: Martín-Rufián, Mercedes, Tosina, Marta, Campos-Sandoval, José A., Manzanares, Elisa, Lobo, Carolina, Segura, J. A., Alonso, Francisco J., Matés, José M., Márquez, Javier
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367983/
https://ncbi.nlm.nih.gov/pubmed/22679499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038380
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