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PolG Inhibits Gastric Cancer Glycolysis and Viability by Suppressing PKM2 Phosphorylation

PURPOSE: Gastric cancer (GC) is the fifth most frequently diagnosed cancer and the third leading cause of cancer-related death. There is a critical need for the development of novel therapies in GC. DNA polymerase gamma (PolG) has been implicated in mitochondrial homeostasis and affects the developm...

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Bibliografische gegevens
Gepubliceerd in:Cancer Manag Res
Hoofdauteurs: Lv, Mengzhu, Zhang, Simeng, Dong, Yuqing, Cao, Liu, Guo, Shu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7896732/
https://ncbi.nlm.nih.gov/pubmed/33623435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S292306
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