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Torsional stress can regulate the unwrapping of two outer half superhelical turns of nucleosomal DNA
Torsional stress has a significant impact on the structure and stability of the nucleosome. RNA polymerase imposes torsional stress on the DNA in chromatin and unwraps the DNA from the nucleosome to access the genetic information encoded in the DNA. To understand how the torsional stress affects the...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7896312/ https://ncbi.nlm.nih.gov/pubmed/33558240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020452118 |
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