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Free energy profiles for unwrapping the outer superhelical turn of nucleosomal DNA

The eukaryotic genome is packaged into a nucleus in the form of chromatin. The fundamental structural unit of chromatin is a protein-DNA complex, the nucleosome, where 146 or 147 base pairs of DNA wrap 1.75 times around a histone core. To function in cellular processes, however, nucleosomal DNA must...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Kono, Hidetoshi, Sakuraba, Shun, Ishida, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854429/
https://ncbi.nlm.nih.gov/pubmed/29505570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006024
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