Differentiating cancer cells reveal early large-scale genome regulation by pericentric domains

Finding out how cells prepare for fate change during differentiation commitment was our task. To address whether the constitutive pericentromere-associated domains (PADs) may be involved, we used a model system with known transcriptome data, MCF-7 breast cancer cells treated with the ErbB3 ligand he...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Krigerts, Jekabs, Salmina, Kristine, Freivalds, Talivaldis, Zayakin, Pawel, Rumnieks, Felikss, Inashkina, Inna, Giuliani, Alessandro, Hausmann, Michael, Erenpreisa, Jekaterina
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2021
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7896032/
https://ncbi.nlm.nih.gov/pubmed/33453273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.01.002
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