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Pharmacokinetics and Pharmacodynamics of Emicizumab in Persons with Hemophilia A with Factor VIII Inhibitors: HAVEN 1 Study
Emicizumab, a bispecific monoclonal antibody, bridges activated factor IX (FIXa) and FX, replacing the function of missing FVIIIa to restore effective hemostasis in persons with hemophilia A (PwHA). Here we assess pharmacokinetic (PK) and pharmacodynamic (PD) biomarkers in PwHA with FVIII inhibitors...
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| 發表在: | Thromb Haemost |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Georg Thieme Verlag KG
2021
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7895541/ https://ncbi.nlm.nih.gov/pubmed/33086400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0040-1717114 |
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