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Evaluation of the Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose of Emicizumab in Healthy Chinese Subjects

This phase 1, open‐label, single‐center study evaluated the pharmacokinetics (PK), pharmacodynamics, safety, and tolerability of single‐dose emicizumab in healthy Chinese males. Overall, 16 subjects received a single subcutaneous dose of 1‐mg/kg emicizumab. Blood samples were obtained before dosing...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: Li, Haiyan, Zhang, Weijiang, Petry, Claire, Li, Lindong, Fernandez, Elena, Kiialainen, Anna, Feng, Sheng, Hsu, Wanling, Li, Li, Wei, Yudong, Schmitt, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818492/
https://ncbi.nlm.nih.gov/pubmed/32433829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.805
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