Evaluation of the Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose of Emicizumab in Healthy Chinese Subjects

This phase 1, open‐label, single‐center study evaluated the pharmacokinetics (PK), pharmacodynamics, safety, and tolerability of single‐dose emicizumab in healthy Chinese males. Overall, 16 subjects received a single subcutaneous dose of 1‐mg/kg emicizumab. Blood samples were obtained before dosing...

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Vydáno v:Clin Pharmacol Drug Dev
Hlavní autoři: Li, Haiyan, Zhang, Weijiang, Petry, Claire, Li, Lindong, Fernandez, Elena, Kiialainen, Anna, Feng, Sheng, Hsu, Wanling, Li, Li, Wei, Yudong, Schmitt, Christophe
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818492/
https://ncbi.nlm.nih.gov/pubmed/32433829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.805
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