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Trideuteromethylation Enabled by a Sulfoxonium Metathesis Reaction

A conceptually novel sulfoxonium metathesis reaction between TMSOI and cost-effective DMSO-d(6) is developed for the efficient generation of a new trideuteromethylation reagent TDMSOI. The new reagent TDMSOI is produced highly efficiently by simply heating a mixture of TMSOI and DMSO-d(6) and direct...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Shen, Zuyuan, Zhang, Shilei, Geng, Huihui, Wang, Jiarui, Zhang, Xinyu, Zhou, Anqi, Yao, Cheng, Chen, Xiaobei, Wang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895502/
https://ncbi.nlm.nih.gov/pubmed/30615462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b03641
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