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Practical implementation of frailty models in Mendelian risk prediction

There are numerous statistical models used to identify individuals at high risk of cancer due to inherited mutations. Mendelian models predict future risk of cancer by using family history with estimated cancer penetrances (age- and sex-specific risk of cancer given the genotype of the mutations) an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genet Epidemiol
Prif Awduron: Huang, Theodore, Gorfine, Malka, Hsu, Li, Parmigiani, Giovanni, Braun, Danielle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895423/
https://ncbi.nlm.nih.gov/pubmed/32506746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22323
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