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Practical implementation of frailty models in Mendelian risk prediction

There are numerous statistical models used to identify individuals at high risk of cancer due to inherited mutations. Mendelian models predict future risk of cancer by using family history with estimated cancer penetrances (age- and sex-specific risk of cancer given the genotype of the mutations) an...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Genet Epidemiol
Päätekijät: Huang, Theodore, Gorfine, Malka, Hsu, Li, Parmigiani, Giovanni, Braun, Danielle
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895423/
https://ncbi.nlm.nih.gov/pubmed/32506746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22323
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