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Frailty Models for Familial Risk with Application to Breast Cancer

In evaluating familial risk for disease we have two main statistical tasks: assessing the probability of carrying an inherited genetic mutation conferring higher risk; and predicting the absolute risk of developing diseases over time, for those individuals whose mutation status is known. Despite sub...

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Detalhes bibliográficos
Main Authors: Gorfine, Malka, Hsu, Li, Parmigiani, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963469/
https://ncbi.nlm.nih.gov/pubmed/24678132
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