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Protective effects of dapagliflozin against oxidative stress-induced cell injury in human proximal tubular cells

Elevated reactive oxygen species (ROS) in type 2 diabetes cause cellular damage in many organs. Recently, the new class of glucose-lowering agents, SGLT-2 inhibitors, have been shown to reduce the risk of developing diabetic complications; however, the mechanisms of such beneficial effect are largel...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zaibi, Nawel, Li, Pengyun, Xu, Shang-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894948/
https://ncbi.nlm.nih.gov/pubmed/33606763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247234
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