Mono‐ and Di‐Fucosylated Glycans of the Parasitic Worm S. mansoni are Recognized Differently by the Innate Immune Receptor DC‐SIGN

The parasitic worm, Schistosoma mansoni, expresses unusual fucosylated glycans in a stage‐dependent manner that can be recognized by the human innate immune receptor DC‐SIGN, thereby shaping host immune responses. We have developed a synthetic approach for mono‐ and bis‐fucosylated LacdiNAc (LDN‐F a...

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Publicado en:Chemistry
Autores principales: Srivastava, Apoorva D., Unione, Luca, Wolfert, Margreet A., Valverde, Pablo, Ardá, Ana, Jiménez‐Barbero, Jesús, Boons, Geert‐Jan
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894523/
https://ncbi.nlm.nih.gov/pubmed/32957164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202002619
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