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Role of Aurora B and Haspin kinases in the metaphase Topoisomerase II checkpoint
DNA Topoisomerase II (TopoII) uses ATP hydrolysis to decatenate chromosomes so that sister chromatids can faithfully segregate in mitosis. When the TopoII enzyme cycle stalls due to failed ATP hydrolysis, the onset of anaphase is delayed, presumably to allow extra time for decatenation to be complet...
Guardat en:
| Publicat a: | Cell Cycle |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7894448/ https://ncbi.nlm.nih.gov/pubmed/33459116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2021.1875671 |
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