Critical implication of the PTEN/PI3K/AKT pathway during BMP2-induced heterotopic ossification

Heterotopic ossification (HO) is characterized by extraskeletal ossification in soft tissue. Thus far, there is a lack of effective drug therapy against HO. Loss of PTEN in osteoblasts has been reported to accumulate bone mass in skeletal development and promote fracture healing in association with...

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: Dong, Jun, Xu, Xiqiang, Zhang, Qingyu, Yuan, Zenong, Tan, Bingyi
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2021
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893754/
https://ncbi.nlm.nih.gov/pubmed/33537834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.11893
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