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TBX1 is required for normal stria vascularis and semicircular canal development

Little is known about the role of TBX1 in post-otocyst stages of inner ear development. Here, we report on mice with a missense mutation of Tbx1 that are viable with fully developed but abnormally formed inner ears. Mutant mice are deaf due to an undeveloped stria vascularis and show vestibular dysf...

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Detalles Bibliográficos
Publicado en:Dev Biol
Main Authors: Tian, Cong, Johnson, Kenneth R.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893642/
https://ncbi.nlm.nih.gov/pubmed/31550482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.09.013
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