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Spontaneous mutations of the Zpld1 gene in mice cause semicircular canal dysfunction but do not impair gravity receptor or hearing functions

The cupula is a gelatinous membrane overlying the crista ampullaris of the semicircular canal, important for sensing rotation of the head and critical for normal balance. Recently the zona pellucida like domain containing 1 protein (ZPLD1, also known as cupulin) was identified in the cupula of fish....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vijayakumar, Sarath, Jones, Sherri M., Jones, Timothy A., Tian, Cong, Johnson, Kenneth R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711997/
https://ncbi.nlm.nih.gov/pubmed/31455802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48835-5
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