Effect of intermittent preventive treatment for malaria with dihydroartemisinin-piperaquine on immune responses to vaccines among rural Ugandan adolescents: randomised controlled trial protocol B for the ‘POPulation differences in VACcine responses’ (POPVAC) programme

INTRODUCTION: Drivers of lower vaccine efficacy and impaired vaccine-specific immune responses in low-income versus high-income countries, and in rural compared with urban settings, are not fully elucidated. Repeated exposure to and immunomodulation by parasite infections may be important. We focus...

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Dettagli Bibliografici
Pubblicato in:BMJ Open
Autori principali: Natukunda, Agnes, Nkurunungi, Gyaviira, Zirimenya, Ludoviko, Nassuuna, Jacent, Oduru, Gloria, Amongin, Rebecca, Kabuubi, Prossy N, Mutebe, Alex, Onen, Caroline, Amongi, Susan, Nakazibwe, Esther, Akello, Florence, Kiwanuka, Samuel, Kiwudhu, Fred, Sewankambo, Moses, Nsubuga, Denis, Kizindo, Robert, Staedke, Sarah G, Cose, Stephen, Webb, Emily, Elliott, Alison M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2021
Soggetti:
Infectious Diseases
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893608/
https://ncbi.nlm.nih.gov/pubmed/33593769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-040427
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