Association of Immunophenotype With Pathologic Complete Response to Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer: A Secondary Analysis of the BrighTNess Phase 3 Randomized Clinical Trial

IMPORTANCE: Adding carboplatin to standard neoadjuvant chemotherapy (NAC) in triple-negative breast cancer (TNBC) likely benefits a subset of patients; however, determinants of benefit are poorly understood. OBJECTIVE: To define the association of molecular subtype, tumor proliferation, and immunoph...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JAMA Oncol
Prif Awduron: Filho, Otto Metzger, Stover, Daniel G., Asad, Sarah, Ansell, Peter J., Watson, Mark, Loibl, Sibylle, Geyer, Charles E., Bae, Junu, Collier, Katharine, Cherian, Mathew, O’Shaughnessy, Joyce, Untch, Michael, Rugo, Hope S., Huober, Jens B., Golshan, Mehra, Sikov, William M., von Minckwitz, Gunter, Rastogi, Priya, Maag, David, Wolmark, Norman, Denkert, Carsten, Symmans, W. Fraser
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Medical Association 2021
Pynciau:
Brief Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893540/
https://ncbi.nlm.nih.gov/pubmed/33599688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2020.7310
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