PIK3CA H1047R Mutation Associated with a Lower Pathological Complete Response Rate in Triple-Negative Breast Cancer Patients Treated with Anthracycline-Taxane–Based Neoadjuvant Chemotherapy

PURPOSE: PIK3CA, encoding for subunit p110a of phosphatidylinositol 3 kinase, is frequently mutated in breast cancer. PIK3CA mutation was predictive for pathological complete response (pCR) in human epidermal growth factor 2 positive breast cancer. This study explores the association of PIK3CA mutat...

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Detalhes bibliográficos
Publicado no:Cancer Res Treat
Main Authors: Guo, Sanxing, Loibl, Sibylle, von Minckwitz, Gunter, Darb-Esfahani, Silvia, Lederer, Bianca, Denkert, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Cancer Association 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373870/
https://ncbi.nlm.nih.gov/pubmed/32019278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2019.497
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