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Puerarin pretreatment attenuates cardiomyocyte apoptosis induced by coronary microembolization in rats by activating the PI3K/Akt/GSK-3β signaling pathway

Coronary microembolization (CME) is associated with cardiomyocyte apoptosis and cardiac dysfunction. Puerarin confers protection against multiple cardiovascular diseases, but its effects and specific mechanisms on CME are not fully known. Hence, our study investigated whether puerarin pretreatment c...

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Опубликовано в: :Korean J Physiol Pharmacol
Главные авторы: Chen, Zhi-Qing, Zhou, You, Huang, Jun-Wen, Chen, Feng, Zheng, Jing, Li, Hao-Liang, Li, Tao, Li, Lang
Формат: Artigo
Язык:Inglês
Опубликовано: The Korean Physiological Society and The Korean Society of Pharmacology 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893491/
https://ncbi.nlm.nih.gov/pubmed/33602885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2021.25.2.147
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