Breviscapine Pretreatment Inhibits Myocardial Inflammation and Apoptosis in Rats After Coronary Microembolization by Activating the PI3K/Akt/GSK-3β Signaling Pathway

PURPOSE: Coronary microembolization (CME) can cause myocardial inflammation, apoptosis and progressive cardiac dysfunction. On the other hand, breviscapine exerts a significant cardioprotective effect in many cardiac diseases although its role and the potential mechanisms in CME remain unclear. Ther...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Chen, Zhi-Qing, Zhou, You, Chen, Feng, Huang, Jun-Wen, Zheng, Jing, Li, Hao-Liang, Li, Tao, Li, Lang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920514/
https://ncbi.nlm.nih.gov/pubmed/33658766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S293382
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