טוען...

Multiple cereblon genetic changes are associated with acquired resistance to lenalidomide or pomalidomide in multiple myeloma

Emergence of drug resistance to all available therapies is the major challenge to improving survival in myeloma. Cereblon (CRBN) is the essential binding protein of the widely used immunomodulatory drugs (IMiDs) and novel CRBN E3 ligase modulator drugs (CELMoDs) in myeloma, as well as certain proteo...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Blood
Main Authors: Gooding, Sarah, Ansari-Pour, Naser, Towfic, Fadi, Ortiz Estévez, María, Chamberlain, Philip P., Tsai, Kao-Tai, Flynt, Erin, Hirst, Marissa, Rozelle, Dan, Dhiman, Paula, Neri, Paola, Ramasamy, Karthik, Bahlis, Nizar, Vyas, Paresh, Thakurta, Anjan
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893409/
https://ncbi.nlm.nih.gov/pubmed/33443552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020007081
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