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The PHP domain of PolX from Staphylococcus aureus aids high fidelity DNA synthesis through the removal of misincorporated deoxyribo-, ribo- and oxidized nucleotides

The X family is one of the eight families of DNA polymerases (dPols) and members of this family are known to participate in the later stages of Base Excision Repair. Many prokaryotic members of this family possess a Polymerase and Histidinol Phosphatase (PHP) domain at their C-termini. The PHP domai...

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Publicat a:Sci Rep
Autors principals: Nagpal, Shilpi, Nair, Deepak T.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893174/
https://ncbi.nlm.nih.gov/pubmed/33603016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83498-1
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