Activated Hepatic Stellate Cells Induce Infiltration and Formation of CD163(+) Macrophages via CCL2/CCR2 Pathway

Background: Activated hepatic stellate cells (aHSCs) regulate the function of immune cells during liver fibrosis. As major innate cells in the liver, macrophages have inducible plasticity. Nevertheless, the mechanisms through which aHSCs regulate macrophages' phenotype and function during liver...

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Vydáno v:Front Med (Lausanne)
Hlavní autoři: Xi, Sujuan, Zheng, Xiaoyan, Li, Xiangyong, Jiang, Yuming, Wu, Yuankai, Gong, Jiao, Jie, Yusheng, Li, Zhanyi, Cao, Jing, Sha, Liuping, Zhang, Min, Chong, Yutian
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7893116/
https://ncbi.nlm.nih.gov/pubmed/33614685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2021.627927
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