Patient-derived xenografts and organoids model therapy response in prostate cancer

Therapy resistance and metastatic processes in prostate cancer (PCa) remain undefined, due to lack of experimental models that mimic different disease stages. We describe an androgen-dependent PCa patient-derived xenograft (PDX) model from treatment-naïve, soft tissue metastasis (PNPCa). RNA and who...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Karkampouna, Sofia, La Manna, Federico, Benjak, Andrej, Kiener, Mirjam, De Menna, Marta, Zoni, Eugenio, Grosjean, Joël, Klima, Irena, Garofoli, Andrea, Bolis, Marco, Vallerga, Arianna, Theurillat, Jean-Philippe, De Filippo, Maria R., Genitsch, Vera, Keller, David, Booij, Tijmen H., Stirnimann, Christian U., Eng, Kenneth, Sboner, Andrea, Ng, Charlotte K. Y., Piscuoglio, Salvatore, Gray, Peter C., Spahn, Martin, Rubin, Mark A., Thalmann, George N., Kruithof-de Julio, Marianna
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892572/
https://ncbi.nlm.nih.gov/pubmed/33602919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21300-6
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