Tissue Treg Secretomes and Transcription Factors Shared With Stem Cells Contribute to a Treg Niche to Maintain Treg-Ness With 80% Innate Immune Pathways, and Functions of Immunosuppression and Tissue Repair

We used functional -omics angles and examined transcriptomic heterogeneity in CD4(+)Foxp3(+) regulatory T cells (Treg) from spleen (s-Treg), lymph nodes (LN-Treg), intestine (int-Treg), and visceral adipose tissue (VAT-Treg), and made significant findings: 1) Five new shared Treg genes including NIB...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhang, Ruijing, Xu, Keman, Shao, Ying, Sun, Yu, Saredy, Jason, Cutler, Elizabeth, Yao, Tian, Liu, Ming, Liu, Lu, Drummer IV, Charles, Lu, Yifan, Saaoud, Fatma, Ni, Dong, Wang, Jirong, Li, Yafeng, Li, Rongshan, Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892453/
https://ncbi.nlm.nih.gov/pubmed/33613572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.632239
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