Direct Visualization of the Binding of Transforming Growth Factor Beta 1 with Cartilage Oligomeric Matrix Protein via High-Resolution Atomic Force Microscopy

This work reports the first direct observations of binding and complex formation between transforming growth factor beta 1 (TGF-β1) and cartilage oligomeric matrix protein (COMP) using high-resolution atomic force microscopy (AFM). Each COMP molecule consists of pentamers whose five identical monome...

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Publié dans:J Phys Chem B
Auteurs principaux: Tran, Victoria, Karsai, Arpad, Fong, Michael C., Cai, Weiliang, Fraley, J. Gabriel, Yik, Jasper H.N., Klineberg, Eric, Haudenschild, Dominik R., Liu, Gang-yu
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891936/
https://ncbi.nlm.nih.gov/pubmed/33052673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.0c07286
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