Metformin doses to ensure efficacy and safety in patients with reduced kidney function

We aimed to develop a metformin dosing strategy to optimise efficacy and safety in patients with reduced kidney function. Metformin data from two studies stratified by kidney function were analysed. The relationship between metformin clearance and kidney function estimates was explored using a regre...

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Bibliographic Details
Published in:PLoS One
Main Authors: Kuan, Isabelle H. S., Wilson, Luke C., Leishman, Jed C., Cosgrove, Samuel, Walker, Robert J., Putt, Tracey L., Schollum, John B. W., Wright, Daniel F. B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891741/
https://ncbi.nlm.nih.gov/pubmed/33600406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246247
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