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Metformin doses to ensure efficacy and safety in patients with reduced kidney function

We aimed to develop a metformin dosing strategy to optimise efficacy and safety in patients with reduced kidney function. Metformin data from two studies stratified by kidney function were analysed. The relationship between metformin clearance and kidney function estimates was explored using a regre...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Kuan, Isabelle H. S., Wilson, Luke C., Leishman, Jed C., Cosgrove, Samuel, Walker, Robert J., Putt, Tracey L., Schollum, John B. W., Wright, Daniel F. B.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891741/
https://ncbi.nlm.nih.gov/pubmed/33600406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246247
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