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Metformin doses to ensure efficacy and safety in patients with reduced kidney function

We aimed to develop a metformin dosing strategy to optimise efficacy and safety in patients with reduced kidney function. Metformin data from two studies stratified by kidney function were analysed. The relationship between metformin clearance and kidney function estimates was explored using a regre...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Kuan, Isabelle H. S., Wilson, Luke C., Leishman, Jed C., Cosgrove, Samuel, Walker, Robert J., Putt, Tracey L., Schollum, John B. W., Wright, Daniel F. B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891741/
https://ncbi.nlm.nih.gov/pubmed/33600406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246247
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