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Metformin doses to ensure efficacy and safety in patients with reduced kidney function

We aimed to develop a metformin dosing strategy to optimise efficacy and safety in patients with reduced kidney function. Metformin data from two studies stratified by kidney function were analysed. The relationship between metformin clearance and kidney function estimates was explored using a regre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kuan, Isabelle H. S., Wilson, Luke C., Leishman, Jed C., Cosgrove, Samuel, Walker, Robert J., Putt, Tracey L., Schollum, John B. W., Wright, Daniel F. B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891741/
https://ncbi.nlm.nih.gov/pubmed/33600406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246247
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